If you, or someone you know, is living with HIV/AIDS, the American Dental Association recommends that dental health care be part of all HIV/AIDS treatment plans. That’s because people living with HIV/AIDS are more susceptible to infections including dental infections, which can affect their overall health. How Does HIV/AIDS Affect the Mouth? Your mouth may be the first part of your body to be affected when infected with HIV. Because infection with HIV will weakened your immune system, this means you will be susceptible to infections and other problems. In your mouth, this can cause pain and tooth loss. People with HIV may experience the following mouth issues: Dry mouth Thrush White lesions on the sides of the tongue (oral …